Epipremnum aureum
Pothos is forgiving, which makes it easy to get lazy with. It tells you when it is thirsty by drooping, then recovers within hours of a drink. The bigger risk is the opposite: soil that never dries between waterings.
Short answer: for a pothos, with the starting settings below (a 6 inch pot with a drainage hole), check the soil about every 6 to 8 days in spring and summer and every 8 to 13 days in winter, and water when the top inch of soil is dry. Give it a full drink until water runs out the bottom.
Your answer
Water when the soil reaches this point
How it shifts through the year
Check the soil about every 6 to 8 days in spring and summer and water only when the top inch of soil is dry. In winter, growth slows and soil stays wet longer, so expect roughly 8 to 13 days between checks. Always confirm with your finger first.
Water slowly until water runs out the drainage holes, then empty the saucer within an hour. The right amount depends on pot size, so go by drainage and how dry the soil is, not a fixed measure. Pothos forgive an occasional missed drink, but not soil that stays soggy.
Drooping is most often thirst, but overwatered roots that cannot take up water look the same. Feel the soil first. If it is dry, water. If it is wet, let it dry and check the roots.
A schedule gives a starting point, but light and season change how fast the soil dries. Use the interval to decide when to check, then water only when the top inch or two is dry.
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Related guides
Estimates use rules of thumb. Always confirm with your finger: push it about an inch into the soil before you water.